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Genetic Testing Interpretation with Opus 23

posted 5 Aug 2016, 04:09 by Tom Greenfield
Genetic testing for the public has been available from the American company 23andMe for some time, but interpretation of the raw data file with numbers and letters is a specialist task. The US FDA has limited the amount of health information that 23andMe can give to consumers, apart from ancestry data which can tell you who you else might be related to out of those who have done the test. Although used extensively for medical research, 23andMe allows users to find out whether their genes are more likely to give them curly hair, blue or green eyes and flush when they drink alcohol. 

Various independent interpretation services have been developed which analyse the 23andMe raw data and highlight important variations on the genes, or genetic mutations, but most of these reports still need an expert to understand the significance of the individual's mutations. Now a new tool for practitioners and researchers called Opus 23 can analyse the raw data in depth, and has many different reporting tools available depending on the area being researched. The software was written and programmed by naturopathic physician Dr Peter D'Adamo. The report features wording that the layperson can more easily understand, written in plain English. 

One useful feature of Opus 23 is that medical studies published on the US National Library of Medicine are extensively referenced for the effects of genetic mutations and for the effects of natural products on gene function. This can be used to devise a personalised prescription of natural medicines for the patient based on scientific research studies. Because these are based on the individual's own genetics, it is something that is more likely to work for them than simply taking a product because it helps others. 

One more thing that Opus 23 does is analyse the genetics of the gut microbiome using a uBiome test, and these results are integrated with the 23andMe test results for the individual to give even greater personalised recommendations.

Tom and Jacqueline Greenfield are editors and curators of the Opus 23 software, adding data and writing descriptions in technical scientific language for the practitioner and in plain English for the patient. They also run an online training course for practitioners wanting to use the software. They use Opus 23 extensively with their patients in their London and Canterbury clinics.